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CALSCALE:GREGORIAN
METHOD:PUBLISH
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TZID:Europe/Vienna
BEGIN:DAYLIGHT
DTSTART:20180325T030000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
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TZNAME:CEST
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DTSTART:20171029T020000
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BEGIN:VEVENT
DTSTAMP:20260424T143405Z
UID:5a81540397219407035795@ist.ac.at
DTSTART:20180301T150000
DTEND:20180301T161500
DESCRIPTION:Speaker: Georg Pabst\nhosted by Gasper Tkacik\nAbstract: Biolog
 ical membranes are well-known for their dynamic structural complexity and 
 have attracted significant research efforts to unravel mechanisms underpin
 ning their function. In this framework lipid-only models serve as valuable
  platforms for studying the functional role of membrane lipids under chemi
 cally well-defined conditions. Of recent we have focused on complex lipid 
 mixtures displaying domains of variable size\, or transmembrane asymmetry\
 , applying small-angle X-ray and neutron scattering experiments in combina
 tion with diverse complementary techniques to interrogate their nanoscopic
  structural and elastic properties. I will highlight some of our recent re
 sults\, including lipid packing in domains of different size and compositi
 on\, passive lipid flip-flop\, and interleaflet coupling in asymmetric lip
 id bilayers. I will detail how such data can be used to predict protein pa
 rtitioning and function in a given lipid environment and discuss experimen
 tal evidence for a tight correlation of membrane elasticity to synergistic
  activity of antimicrobial peptides.
LOCATION:Seminar Room\, Lab Building East\, ISTA
ORGANIZER:andersson@ist.ac.at
SUMMARY:Georg Pabst: Physical insight on cell membrane function from comple
 x mimetics
URL:https://talks-calendar.ista.ac.at/events/1106
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