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DTSTART:20180325T030000
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DTSTART:20171029T020000
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DTSTAMP:20260424T114213Z
UID:5a6742630bf53612275390@ist.ac.at
DTSTART:20180308T090000
DTEND:20180308T100000
DESCRIPTION:Speaker: Jochen Rink\nhosted by Michael Sixt\nAbstract: Some an
 imals have the ability to regenerate body parts lost to injury\, while alr
 eady closely related species are often unable to regenerate. Why regenerat
 ion should remain an exception rather then the rule represents a fascinati
 ng question in the face of survival of the fittest. My lab studies the abi
 lity of planarian flatworms to regenerate complete animals from random tis
 sue fragments as model system for regeneration. In addition\, we are pione
 ering the laboratory culture of regeneration-deficient planarians and have
  established a large live collection with currently > 60 species. Together
 \, these approaches allow us to analyze the molecular mechanisms that orch
 estrate regeneration in the well regenerating model species\, the specific
  changes in the underlying regulatory networks that cause regeneration def
 ects in other species and finally the evolutionary mechanisms that might e
 xplain their natural selection. My talk will illustrate our model taxon ap
 proach by example of the Wnt signaling network\, which we identified both 
 as core mechanism of normal regeneration and as a hot spot in the repeated
  evolution of planarian regeneration defects.
LOCATION:Mondi Seminar Room 2\, Central Building\, ISTA
ORGANIZER:pdelreal@ist.ac.at
SUMMARY:Jochen Rink: Molecular and evolutionary mechanisms in planarian reg
 eneration
URL:https://talks-calendar.ista.ac.at/events/1101
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