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DTSTART:20180325T030000
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DTSTART:20171029T020000
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BEGIN:VEVENT
DTSTAMP:20260424T041201Z
UID:5a533979c5015145538663@ist.ac.at
DTSTART:20180305T090000
DTEND:20180305T100000
DESCRIPTION:Speaker: Thomas Surrey\nhosted by Carl-Philipp Heisenberg\nAbst
 ract: The cytoskeleton provides the backbone for intracellular order which
  is fundamental for cell function. Although most of the important componen
 ts of the cytoskeleton have now been identified\, the design principles un
 derlying the internal organization of cells are still poorly understood.  
 A major challenge is the complexity of cytoskeletal networks combined with
  their thermodynamic non-equilibrium nature. To develop a mechanistic unde
 rstanding of cytoskeletal systems based on simple physical principles\, we
  reverse-engineer dynamic sub-architectures of the human microtubule cytos
 keleton from purified proteins. This powerful quantitative microscopy-base
 d approach allows to identify design principles governing the self-organiz
 ation of distinct cytoskeletal steady-state structures. We will present in
  vitro reconstitutions of networks mimicking different types of architectu
 res of the human microtubule cytoskeleton that are important for cell divi
 sion as cells go through the cell cycle. From these examples\, we will ext
 ract general rules for the organization of dynamic intracellular filament 
 networks.
LOCATION:Big Seminar room Ground floor / Office Bldg West (I21.EG.101)\, IS
 TA
ORGANIZER:pdelreal@ist.ac.at
SUMMARY:Thomas Surrey: Reverse engineering of dynamic microtubule cytoskele
 ton architectures
URL:https://talks-calendar.ista.ac.at/events/1066
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