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TZID:Europe/Vienna
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DTSTART:20180325T030000
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DTSTART:20171029T020000
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BEGIN:VEVENT
DTSTAMP:20260407T163932Z
UID:1517220000@ist.ac.at
DTSTART:20180129T110000
DTEND:20180129T120000
DESCRIPTION:Speaker: Jeong-Ho LEE\nhosted by Gaia Novarino\nAbstract: Mutat
 ions occur during cell division in all somatic lineages due to the unavoid
 able DNA replication errors. Because neural stem cells continue to undergo
  cell division throughout human life\, somatic mutations in human brain ca
 n arise during development and accumulate with the aging process. Although
  somatic diversity is an evident feature of the brain\, the extent of soma
 tic mutations affecting the neuronal structure and function and their cont
 ribution to neurological disorders remain largely unexplored. Recently\, w
 e and other groups have provided the molecular genetic evidence that brain
  somatic mutations indeed lead to the structural and functional abnormalit
 ies of the brain observed in several neurodevelopmental disorders. In this
  symposium\, I will present our recent findings regarding brain somatic mu
 tations as potential molecular lesions underlying various human brain diso
 rders.
LOCATION:Mondi 2\, ISTA
ORGANIZER:Waltraud Kölbl
SUMMARY:Jeong-Ho LEE: Deciphering somatic mutations in human brain disorder
 s
URL:https://talks-calendar.ista.ac.at/events/1037
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