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DTSTART:20170326T030000
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DTSTART:20161030T020000
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DTSTAMP:20260429T024208Z
UID:57209db7e4dbc641660443@ist.ac.at
DTSTART:20170130T160000
DTEND:20170130T171500
DESCRIPTION:Speaker: Patricia Wittkopp\nhosted by Nick Barton\nAbstract: Ge
 netic variation segregating within a species reflects the combined activit
 ies of mutation\, selection\, and genetic drift. In the absence of selecti
 on\, polymorphisms are expected to be a random subset of new mutations\; t
 hus\, comparing the effects of polymorphisms and new mutations provides a 
 test for selection. When evidence of selection exists\, such comparisons c
 an identify properties of mutations that are most likely to persist in nat
 ural populations. We have been investigating how mutation and selection co
 ntribute to variation in cis- and trans-regulatory sequences controlling g
 ene expression by empirically determining the effects of new mutations and
  polymorphisms in Saccharomyces cerevisiae. The latest findings from this 
 work\, including empirical measures of the relationship between changes in
  gene expression\, expression noise\, and fitness\, will be presented and 
 discussed.
LOCATION:Raiffeisen Lecture Hall\, Central Building\, ISTA
ORGANIZER:aeller@ist.ac.at
SUMMARY:Patricia Wittkopp: The Institute Colloquium: Evolution of gene expr
 ession: from mutation to polymorphism
URL:https://talks-calendar.ista.ac.at/events/10
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