Genetics to Revelation
Date
Friday, March 8, 2024 11:00 - 12:00
Speaker
Mario de Bono (ISTA)
Location
Raiffeisen Lecture Hall
Series
Colloquium
Tags
4th year colloquium
Host
Tim Vogels
Contact
Abstract
One of the remarkable findings of Biology is that at a molecular mechanistic level, animals work in similar ways. We aim to discover protein machines that ultimately allow the neural circuits of a worm to properly coordinate its behaviour. To find these machines, we randomly damage the animal's DNA, and identify mutants defective in the behavior we are studying.
Elucidating how a small part contributes to the function of the marvellously complex system that is an animal requires a little imagination and a lot of painstaking detective work. I will describe our analysis of several such machines found from worms to humans.