Spatial and temporal control of synaptic vesicle exocytosis and endocytosis
Date
Tuesday, November 5, 2019 11:00 - 12:00
Speaker
Shigeki Watanabe (Johns Hopkins University)
Location
Mondi Seminar Room 2, Central Building
Series
Seminar/Talk
Tags
Life Sciences Seminar
Host
Peter Jonas
Contact
Synaptic vesicles fuse with the plasma membrane for neurotransmission. Subsequently, these vesicles are retrieved, and new vesicles are reconstituted locally at synapses. However, how exocytosis and endocytosis are controlled spatially and temporally remains enigmatic. We developed novel techniques in electron microscopy to capture membrane and protein dynamics with millisecond temporal resolution. In the seminar, I will discuss our recent progress on when, where, and how vesicles are consumed and recycled at synaptic terminals.