Revisiting and Repurposing the Double Helix
Date
Monday, October 7, 2019 16:00 - 17:00
Speaker
Taekjip Ha (Johns Hopkins University)
Location
Raiffeisen Lecture Hall, Central Building
Series
Colloquium
Tags
Institute Colloquium
Host
Johann Danzl
Contact
DNA is an iconic molecule that forms a double helical structure, providing the basis for genetic inheritance, and its physical properties have been studied for decades. In this talk, I will present evidence that sequence and methylation dependent physical properties of DNA such as flexibility and self-association may be important for biological functions. In addition, I will present a new application of DNA where mechanical modulations of cell behavior can be studied at the single molecule level using rupturable DNA tethers.